Wednesday, April 17, 2013

Dr. Thimme Reflection


During our Skype conversation with Dr. Thimme, he gave us a clearer understanding of Hepatitis C and its treatment. Hepatitis C is a cytolytic virus transmitted through contact with blood. Therefore, it can be common amongst heroin addicts and people given a tainted blood transfusion before the introduction of blood screenings. Four million people in the US have Hepatitis C, yet many do not realize it. It was discovered in 1989 by Michael Halten. This discovery led to the use of blood screening in order to identify potentially harmful discrepancies. In some third world countries, blood screenings are inaccessible due to their relatively high cost. In Egypt, specifically, ten percent of the population is infected with virus. In some regions of Egypt, entire villages are infected due to previous use of a single syringe to vaccinate the whole village. 

The symptoms of Hepatitis C are inflammation of the liver and the formation of scar tissue on the liver (liver cytosis). Unfortunately, liver cytosis can lead to liver cancer. In the world, the average age of diagnosis is 20 years old. However, in Germany, the average age of diagnosis is 40-50 years old with the discovery of liver cytosis. Eighty percent of all Hepatitis C patients do not have complications. The other twenty percent develop liver cytosis. Research has shown that young, pregnant women with Hepatitis C are at a lower risk for developing liver cytosis. 

The virus has been treated using HCV therapy. Primarily, interferon has been prescribed as a remedy. The downside to interferon therapy is that it has flu-like symptoms among other equally undesirable side effects. There are some problems with the current treatment. First, only thirty percent of patients are able to clear the virus. Second, failure of the killer cells is widespread. Three current goals for scientists are: to identify and prevent the cause of killer cell dysfunction, to develop IPN free therapy and to keep symptoms from returning.